When a provider does an esophagogastroduodenoscopy with biopsies but also does removal of a polyp or lesion in another area, besides the biopsy site, can these both be billed 43251 and 43239 with a modifier to unbundle the 43239, since they are different areas?

Also when doing colonoscopies the same scenario? can these be unbundled if it is a different area within the colon?

The NCCI edits bundle.

Thank you